Title of article :
Synthesis and antiprotozoal activity of some new synthetic substituted quinoxalines
Author/Authors :
Xu Hui، نويسنده , , Julie Desrivot، نويسنده , , Christian Bories، نويسنده , , Philippe M. Loiseau، نويسنده , , Xavier Franck، نويسنده , , Reynald Hocquemiller، نويسنده , , Bruno Figadere، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A series of 29 new quinoxalines was synthesized and evaluated in vitro against several parasites (Leishmania donovani, Trypanosoma brucei brucei, and Trichomonas vaginalis). Several of them displayed interesting activities, and particularly four quinoxaline amides showed in vitro antileishmanial properties (IC50 less than 20 μM).
Keywords :
Quinoxalines , Amides , Amines , synthesis , bioassays
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
