Title of article
Synthesis of complex-type glycans derived from parasitic helminths
Author/Authors
Jun Nakano، نويسنده , , Hiromichi Ohta، نويسنده , , Yukishige Ito، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
6
From page
928
To page
933
Abstract
Chemical synthesis of complex-type glycans 1 and 2 derived from eggs of parasitic helminths, Schistosoma mansoni and Schistosoma japonicum, is described. These branched sugar chains were synthesized regio- and stereoselectively by using β-mannosylation, desilylation under high pressure, and glycosylation in frozen solvent as key transformations.
Keywords
Glycosylation , Parasitic helminths , Frozen solvent , Complex-type glycans , glycoprotein
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796492
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