Title of article :
Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives
Author/Authors :
Zi-bin Zhu، نويسنده , , Brett A. Marinelli، نويسنده , , Darren Abbanat، نويسنده , , Barbara D. Foleno، نويسنده , , Todd C. Henninger، نويسنده , , Karen Bush and Osnat Herzberg، نويسنده , , Mark J. Macielag، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A series of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives has been synthesized. Several functional groups were identified as the optimal C3-substituents, and the best compounds in this series possess potent in vitro antibacterial activity against erythromycin-susceptible and erythromycin-resistant bacteria.
Keywords :
macrolide , Antibacterial , antibiotic , erythromycin
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
