Title of article
Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives
Author/Authors
Zi-bin Zhu، نويسنده , , Brett A. Marinelli، نويسنده , , Darren Abbanat، نويسنده , , Barbara D. Foleno، نويسنده , , Todd C. Henninger، نويسنده , , Karen Bush and Osnat Herzberg، نويسنده , , Mark J. Macielag، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
6
From page
1054
To page
1059
Abstract
A series of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives has been synthesized. Several functional groups were identified as the optimal C3-substituents, and the best compounds in this series possess potent in vitro antibacterial activity against erythromycin-susceptible and erythromycin-resistant bacteria.
Keywords
macrolide , Antibacterial , antibiotic , erythromycin
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796517
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