Title of article :
Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity
Author/Authors :
Dahui Zhou، نويسنده , , Boyd L. Harrison، نويسنده , , Uresh Shah، نويسنده , , Terrance H. Andree، نويسنده , , Geoffrey A. Hornby، نويسنده , , Rosemary Scerni، نويسنده , , Lee E. Schechter، نويسنده , , Deborah L. Smith، نويسنده , , Kelly M. Sullivan، نويسنده , , Richard E. Mewshaw، نويسنده ,
Abstract :
The design, synthesis, and structure–activity relationship of two novel classes of benzoxazine derivatives with dual selective serotonin reuptake inhibitors and 5-HT1A receptor activities are described.
