Title of article :
Antiarrhythmic activity of 4,6-di(het)aryl-5-nitro-3,4-dihydropyrimidin-(1H)-2-ones and its effects on arterial pressure in rats
Author/Authors :
Arkadiy O. Bryzgalov، نويسنده , , Margarita P. Dolgikh، نويسنده , , Irina V. Sorokina، نويسنده , , Tatiana G. Tolstikova، نويسنده , , Valentina F. Sedova، نويسنده , , Oleg P. Shkurko، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
The antiarrhythmic activity of 4,6-di(het)aryl-5-nitro-3,4-dihydropyrimidin-(1H)-2-ones toward two types of experimental rat arrhythmia has been studied. With CaCl2 induced arrhythmia model, several agents have demonstrated high antiarrhythmic activity and the lack of influence on arterial pressure of rats.
Keywords :
Antiarrhythmic activity , 6-Di(het)aryl-5-nitro-3 , 4-dihydropyrimidin-(1H)-2-ones , 4 , arrhythmia
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
