Title of article
Quinol fatty alcohols as promoters of axonal growth
Author/Authors
Mazen Hanbali، نويسنده , , Marta Vela-Ruiz، نويسنده , , Dominique Bagnard، نويسنده , , Bang Luu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
2637
To page
2640
Abstract
The synthesis of three series of quinol fatty alcohols (QFAs) and their biological activities on the promotion of axonal growth are described. Interestingly, the 15-(2,5-dimethoxyphenyl)pentadecan-1-ol, the QFA bearing 15 carbon atoms on the side chain (n = 15), shows the most potent promotion of axonal growth in the presence of both permissive and non-permissive naturally occurring substrates such as Sema3A and myelin proteins.
Keywords
Myelin proteins , Sema3A , Axonal growth , Quinol fatty alcohols , Ubiquinol , brain lesion , Glial scar
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796838
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