Title of article :
Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: Preparation of FXR and PPAR ligands
Author/Authors :
Masahiko Kainuma، نويسنده , , Jun-ichi Kasuga، نويسنده , , Shinnosuke Hosoda، نويسنده , , Ken-ichi Wakabayashi، نويسنده , , Aya Tanatani، نويسنده , , Kazuo Nagasawa، نويسنده , , Hiroyuki Miyachi، نويسنده , , Makoto Makishima، نويسنده , , Yuichi Hashimoto، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Pages :
6
From page :
3213
To page :
3218
Abstract :
Novel, potent farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor α (PPARα) agonists were obtained by using a diphenylmethane skeleton as a substitute for a steroid skeleton.
Keywords :
Nuclear receptor ligands , FXR , Drug design , PPAR , Diphenylmethane
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2006
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
796959
Link To Document :
بازگشت