Title of article
Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1
Author/Authors
Baogen Wu، نويسنده , , Kelli Kuhen، نويسنده , , Truc Ngoc Nguyen، نويسنده , , David Ellis، نويسنده , , Beth Anaclerio، نويسنده , , Xiaohui He، نويسنده , , Kunyong Yang، نويسنده , , Donald Karanewsky، نويسنده , , Hong-Yin Chen، نويسنده , , Karen Wolff، نويسنده , , Kimberly Bieza، نويسنده , , Jeremy Caldwell، نويسنده , , Yun He، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
3430
To page
3433
Abstract
The synthesis and preliminary structure–activity relationship of a series of pyrrolidinones are described. These pyrrolidinones have been characterized as novel non-nucleoside reverse transcriptase inhibitors (NNRTIs) which are highly potent against wild-type and drug-resistant human immunodeficiency viruses (HIV-1).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797005
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