Title of article :
Synthesis of Hsp90 dimerization modulators
Author/Authors :
Gabriela Chiosis، نويسنده , , Julia Aguirre، نويسنده , , Christopher V. Nicchitta، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
The synthesis and evaluation of several chemical modulators of heat shock protein 90 (Hsp90) dimerization is presented. These agents may represent useful tools to study the importance of N-terminal dimerization and also to determine subunit interface(s) in Hsp90.
Keywords :
Chemical modulator of dimerization , geldanamycin , HSP90
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
