• Title of article

    3D QSAR studies of N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones: A novel class of antibacterial agents

  • Author/Authors

    B.B. Lohray، نويسنده , , Neha Gandhi، نويسنده , , Brijesh Kumar Srivastava، نويسنده , , Vidya Bhushan Lohray، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2006
  • Pages
    7
  • From page
    3817
  • To page
    3823
  • Abstract
    Three-dimensional QSAR studies for N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones were conducted using TSAR 3.3. The in vitro activities (MICs) of the compounds against Staphylococcus aureus ATCC 25923 exhibited a strong correlation with the prediction made by the model developed in the present study.
  • Keywords
    In vitro MIC , Heat of formation , Arylacryloylpiperazinylphenyloxazolidinones , 3D QSAR , LUMO , Antibacterial agent
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2006
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    797086