Title of article :
3D QSAR studies of N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones: A novel class of antibacterial agents
Author/Authors :
B.B. Lohray، نويسنده , , Neha Gandhi، نويسنده , , Brijesh Kumar Srivastava، نويسنده , , Vidya Bhushan Lohray، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
Three-dimensional QSAR studies for N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones were conducted using TSAR 3.3. The in vitro activities (MICs) of the compounds against Staphylococcus aureus ATCC 25923 exhibited a strong correlation with the prediction made by the model developed in the present study.
Keywords :
In vitro MIC , Heat of formation , Arylacryloylpiperazinylphenyloxazolidinones , 3D QSAR , LUMO , Antibacterial agent
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
