Title of article :
Crystal structure, spectroscopic, and biological study of the copper(II) complex with third-generation quinolone antibiotic sparfloxacin
Author/Authors :
Eleni K. Efthimiadou، نويسنده , , Yiannis Sanakis، نويسنده , , Catherine P. Raptopoulou، نويسنده , , Alexandra Karaliota، نويسنده , , Nikos Katsaros، نويسنده , , George Psomas، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
The neutral mononuclear copper(II) complex with the quinolone antibacterial drug sparfloxacin has been prepared and characterized with IR, UV–vis, and EPR spectroscopies and X-ray crystallography. The interaction of the complex with calf-thymus DNA has also been investigated and the antimicrobial activity has been evaluated against three different microorganisms.
Keywords :
MIC , Interaction with calf-thymus DNA , Quinolones , Sparfloxacin , Cu(II) complex , EPR spectroscopy
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
