Title of article :
Structure of a new cyclic nonapeptide, segetalin F, and vasorelaxant activity of segetalins from Vaccaria segetalis
Author/Authors :
Hiroshi Morita، نويسنده , , Michiko Eda، نويسنده , , Toru Iizuka، نويسنده , , Yusuke Hirasawa، نويسنده , , Mitsuhiro Sekiguchi، نويسنده , , Young Sook Yun، نويسنده , , Hideji Itokawa، نويسنده , , Koichi Takeya، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A new cyclic nonapeptide, segetalin F, has been isolated from the seeds of Vaccaria segetalis and the structure including absolute stereochemistry was elucidated by using 2D NMR and chemical means. A series of segetalins showed a vasorelaxant activity against norepinephrine (NE)-induced contractions of rat aorta.
Keywords :
cyclic peptide , Segetalin F , Vaccaria segetalis , Vasorelaxant activity
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
