Title of article
14β-Hydroxy-10-deacetylbaccatin III as a convenient, alternative substrate for the improved synthesis of methoxylated second-generation taxanes
Author/Authors
Luciano Barboni، نويسنده , , Guido Giarlo، نويسنده , , Roberto Ballini، نويسنده , , Gabriele Fontana، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
3
From page
5389
To page
5391
Abstract
This article describes a new, convenient, improved synthesis of the 2-debenzoyl-2-m-methoxybenzoyl-7-triethylsilyl-13-oxo-14β-hydroxybaccatin III 1,14-carbonate, the key intermediate in the synthesis of two new second-generation antitumor taxanes.
Keywords
Second-generation taxanes , natural products , terpenoids , Antitumor agents , 14?-Hydroxy-10-deacetylbaccatin III
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797393
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