Title of article
Epibatidine isomers and analogues: Structure–activity relationships
Author/Authors
Richard White، نويسنده , , John R. Malpass، نويسنده , , Sandeep Handa، نويسنده , , S. Richard Baker، نويسنده , , Lisa M. Broad، نويسنده , , Liz Folly، نويسنده , , Adrian Mogg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
5
From page
5493
To page
5497
Abstract
Binding affinities for a range of epibatidine isomers and analogues at the α4β2 and α3β4 nAChR subtypes are reported; compounds having similar N–N distances to epibatidine show similar, high potencies.
Keywords
nicotinic receptor subtypes , nAChR affinity , Structure–activity relationships , Epibatidine isomers , Epibatidine analogues
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797413
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