Title of article
New rifabutin analogs: Synthesis and biological activity against Mycobacterium tuberculosis
Author/Authors
José Barluenga، نويسنده , , Fernando Aznar، نويسنده , , Ana-Belén Garc?a، نويسنده , , Mar?a-Paz Cabal، نويسنده , , Juan J. Palacios، نويسنده , , Mar?a-Angela Menéndez، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
6
From page
5717
To page
5722
Abstract
The synthesis, structure, and biological evaluation of a series of novel rifamycin derivatives, Rifastures (RFA) with potent anti-tuberculosis activity are presented. Some of these derivatives showed higher in vitro activity than rifabutin and rifampicin against not only Mycobacterium tuberculosis strains but also against MAC and Mycobacterium kansasii.
Keywords
Rifamycins , Mycobacterium tuberculosis , Rifastures , Rifabutin
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797460
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