Title of article
Kojic acid and its manganese and zinc complexes as potential radioprotective agents
Author/Authors
Saeed Emami، نويسنده , , Seyed Jalal Hosseinimehr، نويسنده , , Seyed Mohammad Taghdisi، نويسنده , , Shahram Akhlaghpoor، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
4
From page
45
To page
48
Abstract
The naturally occurring fungal metabolite kojic acid and its manganese and zinc complexes have been evaluated as potential radioprotectors in mice. Their toxicity and radioprotective activity (survival rate) have been determined and compared with that of WR-2721 (amifostine). The results of in vivo radioprotection showed that these compounds exhibited significant radioprotective effects against lethal dose of γ-irradiation in mice.
Keywords
Kojic acid , Radioprotective agents , ?-irradiation , complex
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797593
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