Title of article :
Synthesis and activity of a potent, specific azabicyclo[3.3.0]-octane-based DPP II inhibitor
Author/Authors :
Olga Danilova، نويسنده , , Bei Li Zhang، نويسنده , , A. Katrin Szardenings، نويسنده , , Brigitte T. Huber، نويسنده , , Jonathan S. Rosenblum، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
A cell permeable DPP II [also known as DPP2, DPP7, and quiescent cell proline dipeptidase (QPP)] inhibitor has been synthesized. The azabicyclo[3.3.0]octane-based inhibitor is potent and selective and elicits very similar quiescent lymphocyte death to previously characterized inhibitors that are not as selective.
Keywords :
Dipeptidyl peptidase
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
