Title of article :
Analogues of 2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone (COTC) with anti-tumor properties
Author/Authors :
Claire L. Arthurs، نويسنده , , Natasha S. Wind، نويسنده , , Roger C. Whitehead، نويسنده , , Ian J. Stratford، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
The syntheses of three novel analogues of the naturally occurring cytotoxic agent COTC are described and the results of bioassays of the target compounds against two lung cancer cell lines are presented.
Keywords :
Anti-tumor , natural product , Synthetic analogue , glutathione transferase , Organo-fluorine
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters