Title of article
Simple criterion for selection of flavonoid compounds with anti-HIV activity
Author/Authors
Veljko Veljkovic، نويسنده , , Jean-François Mouscadet، نويسنده , , Nevena Veljkovic، نويسنده , , Sanja Glisic، نويسنده , , Zeger Debyser، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
7
From page
1226
To page
1232
Abstract
Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity.
Keywords
In silico screening , Anti-HIV compounds , Flavonoids
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797823
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