Title of article :
Evaluation of nitroalkenes as nitric oxide donors
Author/Authors :
Michael J. Gorczynski، نويسنده , , Jinming Huang، نويسنده , , Heather Lee Loughlin، نويسنده , , S. Bruce King، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
Chemiluminescence experiments demonstrate that simple nitroalkenes release low levels of nitric oxide. UV and EPR measurements suggest but cannot confirm direct NO release from nitroalkenes. Given the biological activity of nitrated unsaturated fatty acids, these results suggest the possible metabolic conversion of nitroalkenes to NO.
Keywords :
nitroalkenes , free radicals , Nitric oxide , Nitric oxide donors
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters