Title of article :
Synthesis and antifungal activity of 6-arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones
Author/Authors :
Chung-Kyu Ryu، نويسنده , , Rae-Eun Park، نويسنده , , Mi-Young Ma، نويسنده , , Ji-Hee Nho، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
6-Arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among those tested, many compounds showed good antifungal activity. The results suggest that phthalazine-5,8-diones would be potent antifungal agents.
Keywords :
Phthalazine-5 , 8-dione , Antimicrobial compounds , antifungal , fungi , substitution effects
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
