Title of article :
Epoxygenase eicosanoids: Synthesis of tetrahydrofuran-diol metabolites and their vasoactivity
Author/Authors :
J.R. Falck، نويسنده , , L. Manmohan Reddy، نويسنده , , Kihwan Byun، نويسنده , , William B. Campbell، نويسنده , , Xiu-Yu Yi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
Eight members of a recently identified family of tetrahydrofuran-diols (THFDs), originating from epoxyeicosatrienoic acids (EETs), were prepared stereospecifically from d-(+)-glucose. The THFDs potently induced relaxation of pre-contracted bovine arteries.
Keywords :
Eicosanoids , Epoxygenase , Tetrahydrofuran , Vasorelaxation , EETs
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
