Title of article
Evaluation of N-(phenylmethyl)-4-[5-(phenylmethyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-4-yl]benzamide inhibitors of Mycobacterium tuberculosis growth
Author/Authors
Michael D. Wall، نويسنده , , Michael Oshin، نويسنده , , Gavin A.C. Chung، نويسنده , , Tony Parkhouse، نويسنده , , Andrea Gore، نويسنده , , Esperanza Herreros، نويسنده , , Brian Cox، نويسنده , , Ken Duncan، نويسنده , , Brian Evans ، نويسنده , , Martin Everett، نويسنده , , Alfonso Mendoza، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
2740
To page
2744
Abstract
The biological evaluation of imidazopiperidines as FAS II inhibitors of Mycobacterium tuberculosis growth has been carried out with a view to assessment of potential as lead compounds for the development of a new TB drug. A summary of the hit evaluation and current challenges is described herein.
Keywords
Mycobacterium tuberculosis , InhA , Imidazopiperidines
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798115
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