Title of article :
Phosphonoxins: Rational design and discovery of a potent nucleotide anti-Giardia agent
Author/Authors :
Dae-Hwan Suk، نويسنده , , Dominik Rejman، نويسنده , , Christine C. Dykstra، نويسنده , , Radek Pohl، نويسنده , , Krzysztof W. Pankiewicz، نويسنده , , Steven E. Patterson، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
Phosphonoxins, a new class of synthetic, rationally designed anti-microbial agents, are described. From this class a sub-micromolar inhibitor of Giardia trophozoite growth has been identified.
Keywords :
Giardia , Encystation , Cyst wall synthase , nucleotide
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
