Title of article
Dihydro-[1H]-quinolin-2-ones as retinoid X receptor (RXR) agonists for potential treatment of dyslipidemia
Author/Authors
Bharat Lagu، نويسنده , , Rimma Lebedev، نويسنده , , Barbara Pio، نويسنده , , Maria Yang، نويسنده , , Patricia D. Pelton، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
6
From page
3491
To page
3496
Abstract
A number of RXR modulators with novel structural features were synthesized and screened in the functional assays. The synthesis and the structure–activity relationship within the series of compounds will be presented. Some in vivo data generated in the models for dyslipidemia and diabetes will also be presented.
Keywords
ABCA-1 , RXR , LXR , dyslipidemia , triglycerides
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798260
Link To Document