Author/Authors :
Yasuhiro Igarashi، نويسنده , , Martha E. Trujillo، نويسنده , , Eustoquio Martinez-Molina ، نويسنده , , Saeko Yanase، نويسنده , , Satoshi Miyanaga، نويسنده , , Takamasa Obata، نويسنده , , Hiroaki Sakurai، نويسنده , , Ikuo Saiki، نويسنده , , Tsuyoshi Fujita، نويسنده , , Tamotsu Furumai، نويسنده ,
Abstract :
Two novel anthraquinones, lupinacidins A (1) and B (2), have been isolated from the culture broth of a new endophytic actinomycete belonging to the genus Micromonospora. Lupinacidins were found to show significant inhibitory effects on the invasion of murine colon 26-L5 carcinoma cells without inhibiting cell growth.
Keywords :
Lupinacidin , Micromonospora , antitumor , invasion