Title of article :
Novel ebselen–porphyrin conjugates: Synthesis and nucleic acid interaction study
Author/Authors :
Zhi-Xue Zhang، نويسنده , , Xin Hou، نويسنده , , Daniel Wei-Jing Kwong، نويسنده , , Wai Kwok Wong، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
Novel porphyrins bearing ebselen (2-phenyl-1,2-benzisoselenazol-3[2H]-one) moiety were synthesized and characterized. Their interactions with herring sperm DNA were studied by means of UV–visible, fluorescence, circular dichroism spectroscopy, and gel electrophoresis.
Keywords :
Ebselen , binding mode , HS DNA , Porphyrins
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters