Title of article
Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitors
Author/Authors
John M. Keith، نويسنده , , Leslie A. Gomez، نويسنده , , Ann J. Barbier، نويسنده , , Sandy J. Wilson، نويسنده , , Jamin D. Boggs، نويسنده , , Brian Lord، نويسنده , , Curt Mazur، نويسنده , , Leah Aluisio، نويسنده , , Timothy W. Lovenberg، نويسنده , , Nicholas I. Carruthers، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
4
From page
4374
To page
4377
Abstract
A series of novel and potent 6-heteroaryl-pyrrolidino-tetrahydroisoquinolines with dual histamine H3 antagonist/serotonin transporter inhibitor activity is described. In vitro and in vivo data are discussed.
Keywords
serotonin transporter , Histamine H3 , microdialysis
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798428
Link To Document