Author/Authors :
Sonali Rudra، نويسنده , , Fnu Sangita، نويسنده , , Arti Gujrati، نويسنده , , Manisha Pandya، نويسنده , , Pragya Bhateja، نويسنده , , Tarun Mathur، نويسنده , , Smita Singhal، نويسنده , , Ashok Rattan، نويسنده , , Mohammed Salman، نويسنده , , Biswajit Das، نويسنده ,
Abstract :
Novel oxazolidinone derivatives of the lead compound RBx 8700, containing methylene oxygen- and methylene sulfur-linked substituents at the C5-position, were synthesized. Antibacterial screening of these compounds against a panel of resistant and susceptible Gram-positive and fastidious Gram-negative bacteria gave compounds 2 and 4 as new antibacterial agents.
Keywords :
Nitro-thiophene , Antibacterial , RBx 8700 , oxazolidinone
