Title of article :
Heteroaryl β-tetralin ureas as novel antagonists of human TRPV1
Author/Authors :
Michele C. Jetter، نويسنده , , Mark A. Youngman، نويسنده , , James J. McNally، نويسنده , , Mark E. McDonnell، نويسنده , , Sui-Po Zhang، نويسنده , , Adrienne E. Dubin، نويسنده , , Nadia Nasser، نويسنده , , Ellen E. Codd، نويسنده , , Christopher M. Flores، نويسنده , , Scott L. Dax، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Pages :
4
From page :
6160
To page :
6163
Abstract :
We report on a series of α-substituted-β-tetralin-derived and related phenethyl-based isoquinolinyl and hydroxynaphthyl ureas as potent antagonists of the human TRPV1 receptor. The synthesis and Structure–activity relationships (SAR) of the series are described.
Keywords :
trpv1 , Antagonists , Tetralin ureas
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2007
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
798766
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=798766
بازگشت