Title of article :
Novel heparin/heparan sulfate mimics as inhibitors of HGF/SF-induced MET activation
Author/Authors :
Eun-Ang Raiber، نويسنده , , James A. Wilkinson، نويسنده , , Fabrizio Manetti، نويسنده , , Maurizio Botta، نويسنده , , Jon Deakin، نويسنده , , John Gallagher، نويسنده , , Malcolm Lyon، نويسنده , , Sylvie W. Ducki، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
The synthesis of simple, non-sugar glycosaminoglycan (GAG) mimics has been achieved and the analogues evaluated for their ability to inhibit the activation of the MET receptor by hepatocyte growth factor/scatter factor (HGF/SF).
Keywords :
Heparin/heparan sulfate (H/HS) , Hepatocyte growth factor/scatter factor (HGF/SF) , Glycosaminoglycan (GAG) , Non-carbohydrate mimic , Tyrosine kinase receptor MET
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters