Title of article :
Synthesis of phosphorothioate oligonucleotide–peptide conjugates by solid phase fragment condensation
Author/Authors :
Irmina Diala، نويسنده , , Akira Osada، نويسنده , , Shinji Maruoka، نويسنده , , Takashi Imanisi، نويسنده , , Satoshi Murao، نويسنده , , Taishi Ato، نويسنده , , Hideki Ohba، نويسنده , , Masayuki Fujii، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Pages :
3
From page :
6576
To page :
6578
Abstract :
Phosphorothioate oligonucleotide–peptide conjugates were synthesized by solid phase fragment condensation (SPFC). Arginine rich peptides could be successfully conjugated in 2.8–13.4% isolated yields. All the products were fully characterized by reversed phase HPLC and MALDI–TOF–MS to give satisfactory results.
Keywords :
Phosphorothioate oligonucleotide–peptide conjugates , Solid phase fragment condensation , synthesis
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2007
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
798847
Link To Document :
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