Author/Authors :
Irmina Diala، نويسنده , , Akira Osada، نويسنده , , Shinji Maruoka، نويسنده , , Takashi Imanisi، نويسنده , , Satoshi Murao، نويسنده , , Taishi Ato، نويسنده , , Hideki Ohba، نويسنده , , Masayuki Fujii، نويسنده ,
Abstract :
Phosphorothioate oligonucleotide–peptide conjugates were synthesized by solid phase fragment condensation (SPFC). Arginine rich peptides could be successfully conjugated in 2.8–13.4% isolated yields. All the products were fully characterized by reversed phase HPLC and MALDI–TOF–MS to give satisfactory results.