Title of article :
New ‘chemical probes’ to examine the role of the hFPRL1 (or ALXR) receptor in inflammation
Author/Authors :
Mike Frohn، نويسنده , , Han Xu، نويسنده , , Xiaoming Zou، نويسنده , , Catherine Chang، نويسنده , , Michele McElvaine، نويسنده , , Matthew H. Plant، نويسنده , , Min Wong، نويسنده , , Philip Tagari، نويسنده , , Randall Hungate، نويسنده , , Roland W. Bürli، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Pages :
5
From page :
6633
To page :
6637
Abstract :
We report the development of the novel N-substituted benzimidazole 11 as a potent and selective human formyl peptide receptor-like 1 (hFPRL1) agonist. This compound and its less active enantiomer 12 were identified as useful tools for studying receptor function in vitro.
Keywords :
IL-6 , Neutrophil migration , GPCR , Benzimidazole , hFPRL1
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2007
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
798859
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=798859
بازگشت