Title of article :
Solid-phase synthesis and biological evaluation of a uridinyl branched peptide urea library
Author/Authors :
Dianqing Sun، نويسنده , , Victoria Jones، نويسنده , , Elizabeth I. Carson، نويسنده , , Robin E.B. Lee، نويسنده , , Michael S. Scherman، نويسنده , , Michael R. McNeil، نويسنده , , Richard E. Lee and Stephen W. White، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
A 1000-member uridinyl branched peptide library was synthesized on PS-DES support using IRORI technology. High-throughput screening of this library for anti-tuberculosis activity identified several members with a MIC90 value of 12.5 μg/mL.
Keywords :
Mureidomycins , solid-phase synthesis , IRORI technology , Anti-tuberculosis activity , antibiotic , Uridine-based library , tuberculosis
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
