• Title of article

    Thiophene containing triarylmethanes as antitubercular agents

  • Author/Authors

    Maloy Kumar Parai، نويسنده , , Gautam Panda، نويسنده , , Vinita Chaturvedi، نويسنده , , Y.K. Manju، نويسنده , , Sudhir Sinha، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2008
  • Pages
    4
  • From page
    289
  • To page
    292
  • Abstract
    A new series of thiophene containing triarylmethane derivatives were synthesized from the Friedel–Crafts alkylation of diarylcarbinols followed by incorporation of amino alkyl chains. These were evaluated against Mycobacterium tuberculosisH37Rv and showed the activity in the range of 3.12–12.5 μg/mL in vitro.
  • Keywords
    Thiophene , antitubercular , Friedel–Crafts alkylation
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2008
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    798965