Title of article
Design and synthesis of a fluorescent muscarinic antagonist
Author/Authors
Lyn H. Jones، نويسنده , , Amy Randall، نويسنده , , Carolyn Napier، نويسنده , , Mike Trevethick، نويسنده , , Sasha Sreckovic، نويسنده , , Jessica Watson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
3
From page
825
To page
827
Abstract
The design and concise synthesis of a fluorescent tolterodine-BODIPY (boron dipyrromethene) conjugate is described which possesses potent antimuscarinic activity. This derivative illustrates proof-of-concept for the preparation of other useful fluorophoric antimuscarinic agents which have potential utility in receptor occupancy studies and high throughput screens.
Keywords
fluorescence , BODIPY , Tolterodine , Antimuscarinic
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799068
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