Title of article
Thiosemicarbazones active against Clostridium difficile
Author/Authors
Cait Costello، نويسنده , , Tarja Karpanen، نويسنده , , Peter A. Lambert، نويسنده , , Preena Mistry، نويسنده , , Katy J. Parker، نويسنده , , Daniel L. Rathbone، نويسنده , , Jiangmeng Ren، نويسنده , , Laura Wheeldon، نويسنده , , Tony Worthington، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
1708
To page
1711
Abstract
A set of closely related furylidene thiosemicarbazones was prepared and screened against various clinically important Gram-positive bacteria. One compound containing an ethylene spacer and a 5-nitrofuryl group was found to have promising activity against Clostridium difficile.
Keywords
Thiosemicarbazone , Clostridium difficile , antimicrobial , Nitrofuran
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799235
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