Title of article :
Separate synthesis and evaluation of glucitol bis-phosphate and mannitol bis-phosphate, as competitive inhibitors of fructose bis-phosphate aldolases
Author/Authors :
Charles-Gabin Mabiala-Bassiloua، نويسنده , , Magdalena Zwolinska، نويسنده , , Helene Therisod، نويسنده , , Jurgen Sygusch، نويسنده , , Michel Therisod، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
We report the first unambiguous syntheses of glucitol-1,6-bis-phosphate and mannitol-1,6-bis-phosphate and their competitive inhibition of various fructose bis-phosphate aldolases.
Keywords :
Enzymes inhibitors , aldolase , Fructose-bis-phosphate , glycolysis , Mannitol-bis-phosphate , Hexitol-bis-phosphate , Glucitol-bis-phosphate
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters