Title of article
Rhodamine-based fluorogenic probe for imaging biological thiol
Author/Authors
Aya Shibata، نويسنده , , Kazuhiro Furukawa، نويسنده , , Hiroshi Abe، نويسنده , , Satoshi Tsuneda، نويسنده , , Yoshihiro Ito، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
2246
To page
2249
Abstract
We have developed a new fluorescent probe for biological thiol. The probe was synthesized by the modification of the 2,4-dinitrobenzenesulfonyl group with rhodamine 110. The selective detection of thiol species such as cysteine or glutathione was achieved in biological conditions. Moreover, the probe was successfully applied to the imaging of thiol species in living human cells.
Keywords
thiol , synthesis , probe , imaging , fluorescence
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799333
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