Title of article
Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens
Author/Authors
Govindasami Periyasami، نويسنده , , Raghavachary Raghunathan، نويسنده , , Gangadharan Surendiran، نويسنده , , Narayanasamy Mathivanan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
2342
To page
2345
Abstract
A series of novel dispirooxindolopyrrolizidine derivatives have been synthesized through 1,3-dipolar cycloaddition reaction of azomethine ylide generated from proline and isatin with the dipolarophile (E)-2-arylidine-1-keto carbazoles. The synthesized cycloadducts were evaluated for antimicrobial activities. Compounds 7d and 7e showed relatively good antibacterial and antifungal activities.
Keywords
1 , azomethine ylide , 3-dipolar cycloaddition , Microwave , Pyrrolizidine
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799354
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