Title of article
Improved synthesis of antibacterial 3-substituted 6-anilinouracils
Author/Authors
Niels Svenstrup، نويسنده , , Alexander Kuhl، نويسنده , , Kerstin Ehlert، نويسنده , , Dieter H?bich، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
3215
To page
3218
Abstract
3-Substituted 6-anilinouracils, presently the most promising class of inhibitors of the bacterial DNA polymerase in Gram-positive bacteria, have been prepared by a general and straightforward three-step procedure starting from a readily available 1-benzyloxymethyl-protected derivative of 6-chlorouracil.
Keywords
Gram-positive bacteria , Resistance , Antibacterials , DNA polymerase IIIC , Anilinouracils
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799533
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