Title of article :
Antibacterial activity in serum of the 3,5-diamino-piperidine translation inhibitors
Author/Authors :
Yuefen Zhou، نويسنده , , Chun Chow، نويسنده , , Douglas E. Murphy، نويسنده , , Zhongxiang Sun، نويسنده , , Thomas Bertolini، نويسنده , , Jamie M. Froelich، نويسنده , , Stephen E. Webber، نويسنده , , Thomas Hermann، نويسنده , , Daniel Wall، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
Translation inhibitors of the 3,5-diamino-piperidine series act as aminoglycoside mimetics that inhibit bacterial growth. Here we show antibacterial SAR in the presence and absence of serum with a particular focus toward Pseudomonas aeruginosa.
Keywords :
Decoding site , 3 , 5-Diamino-piperidine , aminoglycosides , antibiotics , Translation inhibitors , 2-Deoxy-streptamine , ribosome
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
