Author/Authors :
S. Bogen، نويسنده , , A. Arasappan، نويسنده , , W. Pan، نويسنده , , Jesse S. Ruan، نويسنده , , A. Padilla، نويسنده , , A.K. Saksena، نويسنده , , V. Girijavallabhan، نويسنده , , F.G. Njoroge، نويسنده ,
Abstract :
Substitutions on the P1 cyclobutyl side chain of SCH 503034 were studied by introduction of hydroxyl and fluoro substituents. Additionally, effects of fluoro substitution on other P1 moieties were evaluated.
Keywords :
pK properties , HCV protease inhibitor , Fluorinated P1 , SCH 503034
