The chemical and hydroxyl radical scavenging activity changes of ginsenoside-Rb1 by heat processing

The chemical and hydroxyl radical (radical dotOH) scavenging activity changes of ginsenoside Rb1 (Rb1) by heat processing were investigated in this study. Rb1 was changed into 20(S)-Rg3, 20(R)-Rg3, Rk1, and Rg5 by heat processing through glucosyl elimination and epimerization of carbon-20 by SN1 reaction. The glucosyl moiety, separated from Rb1, made Maillard reaction product (MRPs) with glycine. The generations of 20(S)-Rg3 and MRPs were related to the increased radical dotOH scavenging activity of Rb1 by heat processing.