Title of article
Small, non-peptide C5a receptor antagonists: Part 2
Author/Authors
Julian Blagg، نويسنده , , Charles Mowbray، نويسنده , , David Pryde، نويسنده , , Gary Salmon، نويسنده , , David Fairman، نويسنده , , Esther Schmid، نويسنده , , Kevin Beaumont، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
5605
To page
5608
Abstract
Starting from 2, several highly potent C5a receptor antagonists were synthesised through α-amide substitution. Attempts to increase the polarity of these compounds through the introduction of basic centres or incorporation into weakly basic heterocycles is described.
Keywords
C5a receptor , Antagonists , inflammation , complement
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800068
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