Title of article :
Small, non-peptide C5a receptor antagonists: Part 2
Author/Authors :
Julian Blagg، نويسنده , , Charles Mowbray، نويسنده , , David Pryde، نويسنده , , Gary Salmon، نويسنده , , David Fairman، نويسنده , , Esther Schmid، نويسنده , , Kevin Beaumont، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
Starting from 2, several highly potent C5a receptor antagonists were synthesised through α-amide substitution. Attempts to increase the polarity of these compounds through the introduction of basic centres or incorporation into weakly basic heterocycles is described.
Keywords :
C5a receptor , Antagonists , inflammation , complement
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
