Title of article
Synthesis and immunostimulatory properties of the phosphorothioate analogues of cdiGMP
Author/Authors
Hongbin Yan، نويسنده , , Xiaolu Wang، نويسنده , , Rhonda KuoLee، نويسنده , , Wangxue Chen، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
5631
To page
5634
Abstract
The synthesis of mono- and bisphosphorothioate analogues of 3′,5′-cyclic diguanylic acid (cdiGMP) via the modified H-phosphonate chemistry is reported. The immunostimulatory properties of these analogues were compared with those of cdiGMP.
Keywords
Vaccine adjuvant , cdiGMP , Immunostimulation , phosphorothioate
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800074
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