Title of article :
Synthesis of 3,6-bicyclolides: A novel class of macrolide antibiotics
Author/Authors :
Yonghua Gai، نويسنده , , Datong Tang، نويسنده , , Guoyou Xu، نويسنده , , Zhigang Chen، نويسنده , , Alexander Polemeropoulos، نويسنده , , Zhe Wang، نويسنده , , Yat Sun Or، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
The synthesis of 3,6-bicyclolides from erythromycin A oxime is described. This novel class of bridged bicyclic macrolides demonstrates potent in vitro and in vivo activities against a broad spectrum of bacteria including resistant respiratory tract pathogens.
Keywords :
3 , 6-Bicyclolide , MIC , Antibacterial
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
