Title of article :
Synthesis of C4-fluorinated solamins and their growth inhibitory activity against human cancer cell lines
Author/Authors :
Naoto Kojima، نويسنده , , Hiromi Hayashi، نويسنده , , Satoshi Suzuki، نويسنده , , Hiroaki Tominaga، نويسنده , , Naoyoshi Maezaki، نويسنده , , Tetsuaki Tanaka، نويسنده , , Takao Yamori، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
C4-Fluorinated analogues of solamin, an antitumor acetogenin, were synthesized and investigated for their antitumor activities against 39 tumor cell lines. C4-Fluorinated solamins showed more potent growth inhibitory activity against cancer cell lines than solamin.
Keywords :
Antitumor agents , Structure–activity relationships , Fluorinated analogues , Annonaceous acetogenins
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
