• Title of article

    Design and synthesis of new potent human cytomegalovirus (HCMV) inhibitors based on internally hydrogen-bonded 1,6-naphthyridines

  • Author/Authors

    Laval Chan، نويسنده , , Tomislav Stefanac، نويسنده , , Jean-François Lavallée، نويسنده , , Haolun Jin، نويسنده , , Jean Bédard، نويسنده , , Suzanne May، نويسنده , , Guy Falardeau، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    103
  • To page
    105
  • Abstract
    1,6-Naphthyridine-2-carboxylic acid benzylamides are potent anti-HCMV compounds. Replacement of the amide moiety by other groups containing internal hydrogen bonds was undertaken to extend the SAR. Our results indicated that the urea derivatives showed very good activity.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2001
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    800287