Design and synthesis of sialyl lewis x mimics as e-selectin inhibitors
Author/Authors :
Neelu Kaila، نويسنده , , Bert E. Thomas IV، نويسنده , , Paresh Thakker، نويسنده , , Juan C. Alvarez، نويسنده , , Raymond T. Camphausen، نويسنده , , Deidre Crommie، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Pages :
5
From page :
151
To page :
155
Abstract :
The design and synthesis of novel β-C-mannosides that inhibit the binding of sialyl Lewis x to E-selectin are described. Compounds that contained a phenyl substituent at the C-6 position were found to have increased potency.
